From Albany:

Take I-90 West to exit 25A. Take I-88 to Exit 22. Go right onto Route 7 for a mile. Turn left at Caverns Road. The Iroquois Indian Museum is on the right after about a mile.

 

From New York City:

Take NY State Thruway North to exit 21 (Catskill). Take Route 23 West to Route 145. Turn on Route 7. Turn left at Caverns Road. The Iroquois Indian Museum is on the right after about a mile.

 

From the West:

Take NY State Thruway East to exit 29 (Canajoharie). Take Route 10 South to Route 7. Turn left at Caverns Road. The Iroquois Indian Museum is on the right after about a mile.

 

From the Southwest:

Take I-88 from Binghamton East to Exit 22 for NY 145. Left at NY 145 N. Turn Right on NY 7E. Turn left on Caverns Road after a mile. The Iroquois Indian Museum is on the right after about a mile